Neighbour R. The Inner Consultation. Feinstein AR. Symptoms as an index of biological behaviour and prognosis in human cancer. Delays during stages of referral diagnosis and treatment of colorectal cancer: their relationship to mortality. Prognostic factors in carcinoma of the colon and rectum. Site, emergency and duration of symptoms in the prognosis of colorectal cancer.
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Duration of colorectal cancer symptoms and survival: the effect of confounding clinical and pathological variables. Eur J Cancer. Relationship of symptom duration and survival in patients with colorectal carcinoma. Eur J Surg Oncol. Symptom duration and survival prospects in carcinoma of the rectum. Surg Gynecol Obstet. Delay in diagnosis and treatment of symptomatic colorectal cancer.
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Cancer of the right colon. An analysis of patients. Prognosis in relation to symptom duration in colon cancer. Diagnostic accuracy and diagnostic delay in carcinoma of the large bowel. NZ Med J. Diagnosis and survival in car- cinoma of the large bowel. Aust NZ J Surg. Colorectal cancer in New Zealand: a Wellington study.
Colorectal cancer. A study of patients. The importance of symptom duration in relation to prognosis of carcinoma of the large intes- tine. Khubchandani M. Relationship of symptom duration and survival in patients and carcinoma of the colon and rectum. Survival of colorectal cancer patients in relation to duration of symptoms and other prognostic factors. Wessex Colorectal Cancer Audit.
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Patient delay in cancer. N Eng J Med. Colorectal cancer: incidence delay in diagnosis and stage of disease. Eur J Cancer Clin Oncol. Rowe-Jones D, Aylett S. Delay in treatment in carcinoma of colon and rectum. Israel J Med Sci. J Epi- demiol Community Health. Changing patterns of colorectal cancer in a regional teaching hospital.
Ann R Coll Surg Engl. Does early diagnosis and prompt treat- ment of symptomatic colorectal cancer improve survival. Gut ;42 suppl 1 : A Macdonald I. Biological predeterminism in human cancer. The individual basis of biologic variability in cancer. Correlation of the prognosis of obstruct- ing colorectal carcinoma with clinical and pathologic variables.
Symptom duration and pathologic staging of colorectal cancer. Duration of symptoms and prognosis of carcinoma of the colon and rectum. Slaney G. Results of treatment of carcinoma of the colon and rectum. In: Irvine WT, ed.
Modern Trends in Surgery 3. London: Butterworths; — Presentation, duration of symptoms and staging of colorectal carcinoma. Early diagnosis in col- orectal cancer. J R Coll Surg Edinb.
Relationship of survival to stage of the tumour and duration of symptoms in colorectal cancer. Goodman D, Irvin TT. Delay in the diagnosis and prognosis of carcinoma of the right colon.
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Delay in diagnosis and treatment of colorectal cancer of colorectal cancer: does it affect outcome? Muir Gray JA. New York: Churchill Livingstone; Marshall KG. How much harm? Physical psy- chological and social harm. Can Med Assoc. Increased absen- teeism from work after detection and labelling of hypertensive patients. Labelling in hyperten- sion: a review of the behavioural and psychological consequences.
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J Chron Dis. Williams CB. Br Med Bull. Gastrointest Endosc Clin N Am. Complications of barium enema examinations: a survey of UK consultant radiologists to Clin Radiol. Clinical presentation of diseases of the large bowel.
A detailed study of patients. Gastroenterology 22— Characteristics of the change in bowel habit in patients with colorectal cancer. Cancer Research UK. Large Bowel Cancer Factsheet. April Ritchie 1. Introduction Colorectal cancer is the third most-common malignancy in the United Kingdom; there are approximately 32, new cases and 17, deaths in the United Kingdom per annum.
Colorectal cancer is equally prevalent in men and women, usually occurring in later life 60—70 years of age. Prog- nosis is dependant upon stage of disease at presentation. Although the incidence and mortality of colorectal cancer have remained static for the last 40 years, there is a recent trend showing a slight decline in incidence and mortality in both the United Kingdom and the United States. Surgery remains the mainstay of treatment for colorectal cancer, but early diagnosis of the disease provides an opportunity to improve outcome. Early diagnosis of colorectal cancer makes it more likely that the tumour can be completely removed and thereby improves the chance of cure.
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